1997 and 2004 treatment for ed . Evaluation of the most promising Therapeutic Targets in patients with biliary tract cancer determiningThe epidermal growth factor receptor and the human epidermal growth factor receptor 2 involved in the carcinogenesis of many tumors. Therapeutic molecules targeting EGFR and HER2 for the treatment of for the treatment of colorectal, lung, head and neck cancer, among others. It is not known whether EGFR and HER2 overexpressed in advanced biliary tract cancer and therefore can therapeutic targets therapeutic targets in these cancers. Results show that EGFR overexpression is frequent in BTC in contrast, HER2 overexpression and gene amplification is a rare occurrence They concluded that routine testing and therapeutic targeting of HER2 does not seem to be in patients useful with BTC, while targeting EGFR may be promising.

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